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KMID : 0371320050690060476
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Journal of the Korean Surgical Society
2005 Volume.69 No. 6 p.476 ~ p.481
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Analysis of Prognostic Factors after Surgery for Gallbladder Cancer
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이강연/Lee KY
안승익/최윤미/이건영/조영업/최선근/허윤석/김세중/홍기천/신석환/김경래/우제홍/Ahn SI/Choi YM/Lee KY/Cho YU/Choi SK/Hur YS/Kim SJ/Hong KC/Shin SH/Kim KR/Woo ZH
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Abstract
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Purpose: Gallbladder cancer, which is the most common malignancy of the biliary tract, is frequently associated with poor prognosis. The aim of this study was to evaluate outcomes with gallbladder cancer according to the surgical treatment, pathologic stage, and prognostic factors.
Methods: The medical records of 52 consecutive patients with gallbladder cancer treated at our institution from June 1996 through June 2005 were reviewed retrospectively. Survival was analyzed using the Kaplan-Meier method (mean followed period 60 months) and the log-rank test. Prognostic factors were analyzed using Cox regression.
Results: Mean patient age was 67 years. Fiftysix percent of patients were female. Twentyeight patients (56%) underwent curative resection (5 simple cholecystectomies and 23 radical cholecystectomies). There were no procedure-related deaths. The Overall 5-year survival was 18%. Patients who underwent curative resection had a higher 5-year survival rate (40%) than patients who underwent palliative surgery (0%; P=0.0001). The palliative surgery, high T stage, positive lymph node metastasis were significant factors predictive of worse survivial.
Conclusion: The good long-term survival may be achieved by an early diagnosis and radical resection. (J Korean Surg Soc 2005;69:476-481)
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